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Bile acid sequestrants are usually used with statins or with nicotinic acid see Lipid Disorders:Low HDL to augment LDL cholesterol reduction and are the drugs of choice for women who are or are planning to become pregnant.
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For the purpose of the Cincinnati Children's Hospital Medical Center's Heart Encyclopedia, the focus is on backup or excessive blood flow into the lungs, which is the most common use of the term in pediatrics.